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Pathophysiology of Appendicitis


Appendicitis is usually caused by blockage of the lumen of the appendix. Obstruction causes the mucus produced by mucous appendix suffered dam. The longer the mucus is more and more, but the elastic wall of the appendix has limitations that lead to increased intra-luminal pressure. These pressures will impede the flow of lymph resulting in mucosal edema and ulceration. At that time there was marked focal acute appendicitis with epigastric pain.

When mucus secretion continues, the pressure will continue to increase. This will cause venous obstruction, increased edema and bacteria will penetrate the wall so that the inflammation of the peritoneum arising widespread and can cause pain in the lower right abdomen is called acute suppurative appendicitis.

If the flow is disrupted arterial wall infarction will occur followed by gangrene appendix. This stage is called appendicitis ganggrenosa. If the appendix wall fragile, there will be a perforation, called perforated appendicitis.

When the process is slow, the omentum and the adjacent bowel will move toward the appendix to appear appendicularis infiltrates.

In children because it shortens the omentum and appendix is longer, thinner walls. The situation is coupled with the immune system that is still less easy to occur perforation, whereas in the elderly prone to occur because there is blood vessel disorders.

Pathophysiology of Appendicitis

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